TOTALBIOLOGIC.com
What is the Total Biologic?  It is using your own cells to help treat disease and injury.  Watch the video below to explore your body's cells.
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Is 2018 the year you stop living with pain?
Our biology is incredible! Learn how your body uses it's own cells to regenerate.  
No physician in history has ever healed a patient. Only the cells of the patient can heal the patient. Only cells know how to close wounds naturally. The best a physician can do is to move obstacles out of the way, supply materials to injured areas and leave the fight against disease and injury to the cells...
Platelets are the cells that circulate within our blood and bind together when they recognize damaged blood vessels. Platelets, the smallest of our blood cells, can only be seen under a microscope. They’re literally shaped like small plates in their non-active state. A blood vessel will send out a signal when it becomes damaged...
The use of amniotic tissue has been documented in published literature since the early 1900s. Amniotic membrane has been the subject of many scientific publications evaluating its use in the: 
• Modulation of Inflammation
• Reduction of Scar Tissue Formation
• Enhanced Healing of Soft Tissue.
The Total Biologic doctor believes biologics offers an enhanced and accelerated healing in certain diseases and injuries.  The custom treatment plans, developed with the patient, are designed from the ground up.  Depending on best treatments for your case, a Total Biologic Doctor  could include one or many different biologic modalities.  
Does Regenerative Medicine work on all parts of the body?
Pain and injury can occur at anytime to any part of your body.  The natural make up of your anatomy is designed to be pain free.   
PRP and Platelet Rich Plasma is used by physicians to treat many types of injuries.  Orthopedic,  Musculoskeletal, Sports Medicine, Pain Management, Physiatry,  Family Practice, Interventional Radiology are some of the physicians that use biologics in their practice.
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Knee
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Hip
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Shoulder
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Spine
Prior to any Regenerative Medicine treatment, understand your options with your doctor.  
Before any regenerative medicine treatment option is finalized, sometimes other changes in lifestyle or habits might help.  These include weight loss, load modification, physical therapy, patient education, topical agents, analgesics, and NSAIDS. 

After these options have been exhausted, treatment options historically included corticosteroid injections to numb pain then surgery if all else failed.   Now, we know stem cells and prp from our body have tremendous healing capabilities that used to be ignored.

During this initial exploration of treatment options, many times using devices like the T:25 Knee sleeve helps solve the issue.  This sleeve applies topical compression on specific muscles in order to stimulate neuromuscular communication and enhance proprioception. This naturally enhances performance while reducing risk of injury
After traditional options haven't produced the desired result, what are my Biologic Options?  PRP is a great first option.
Sometimes, our body needs help to repair itself.  PRP essentially does that.  The biologic mechanism that PRP kick starts, many times helps reduce pain, heal chronic injuries, and gets you back to living you life better and fuller than ever before.  Sometimes one injection is all you will need.  Other times, multiple injections is necessary to completely heal your injury.

Platelet Rich Plasma (PRP) is concentrated from your own blood. Your blood is a robust source of healing components, such as white blood cells, and bioactive proteins, such as growth factors and Stem cell markers. These cells are vital for tissue regeneration and repair. Platelets were once thought of being responsible for only clotting but have been scientifically proven to be a reservoir of these vital healing component. With advanced techniques we are able to concentrate these regenerative healing cells in a simple outpatient setting and accelerate the healing process.
Pure PRP® is the only Platelet Rich Plasma system that gives you the choice of flexibility; to process with or without neutrophils & RBCs (Protocol A and Protocol B). 

Protocol A processes Pure PRP® without red blood cells or neutrophil granulocytes. This protocol is used when powerful healing without inflammatory activity is required at the application site. This protocol is also the low viscosity solution to a viable PRP product, providing very high concentrations of platelets in a bath of non-viscous plasma. This protocol has also been reported to reduce the potential for pain at the application site. It is the most frequently used protocol.
Protocol B  processes Pure PRP® with low red blood cell counts and very high cytokine activity and neutrophil cell recoveries. This protocol is used when the phagocytic powers of neutrophils are needed to help fight infectious processes at the application site. This protocol produces the highest chemoattractant activity and significantly increases regeneration potential. Once the neutrophils have completed phagocytosis, they become apoptic cells and are subsequently removed, thereby also eliminating the inflammatory activity.  

The neutrophil is the most abundant leukocyte in the blood. One of the first lines of immune defense, neutrophils harbor a mix of weaponry to fight off bacteria and fungi.The surface receptors on neutrophils stimulate pro-inflammatory interleukins through chemotaxis.This process causes neutrophils to migrate and populate sites of inflammation. This phenomena is undesirable for many physicians providing injection therapy. For patients experiencing joint pain or injury, treatment protocols usually focus on minimizing inflammation as part of a complete recovery regimen. Pure PRP® is the only PRP that provides significant growth factor concentrations without the inflammatory neutrophils.


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PRP for Achilles Tendon Pain
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PRP for Peroneal Tendonitis
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PRP for Plantar Fasciitis
Stem Cell treatments are also an option 
Stem Cells are found basically everywhere in our body.  But in certain places, these cells are more concentrated and offer a healing potential unlike any man made pharmaceutical or device.  The stem cells are harvested from two main areas, from our bone marrow and from our adipose (fat).  Depending on the injury or condition you have, stem cells from bone marrow or adipose might be included in your treatment plan.

Bone marrow cells reside deep inside bone cavities in the most protected part of the body and are redundant throughout the organism. This preferential status reflects the primary role these cells play in the survival of the organism.  Tissue repair is a dynamic self-organizing process that relies on cell mobility and growth factor production from cells within a biologic scaffold. 
Platelets and Cells from Peripheral Blood Initiate the Inflammatory Process of the Healing Cascade and release cytokines to cause marrow cells to mobilize and home to the injury site (vasculogenesis).
Marrow stem cell and marrow complimentary cell mediated vasculogenesis and cell-to-cell contact with immune system stem cells transition the Healing Cascade from the inflammatory phase to the proliferation and remodeling phase.

Adipose is used in regenerative medicine procedures because mesenchymal stem cells can be isolated from almost every tissue in the human body. The central connecting aspect to explain this fact is that all of these tissues are vascularized and that every blood vessel in the body has mesenchymal cells in abluminal locations. These perivascular cells can be summarily called Pericytes.
Adipose-Derived MSCs are being used therapeutically because they undergo homing to sites of inflammation or tissue injury and they secrete massive levels of bioactive agents that are both immunomodulatory and trophic.

Concentrated Bone Marrow is designed to provide
significant concentrations of CFU-F, CD34+, and total nucleated cell counts. CD34+ are cell markers for hematopoietic stem cells. These are the primary
multipotent cells that replenishes all blood cell types. These cells are crucial for the regenerative processes needed for active tissue repair. In addition to these cells are CFU-F, which are representative of mesenchymal stem cells.
Mesenchymal stem cells (MSC) are multipotent stromal cells that can differentiate into a variety of cell types, including cartilage, bone and adipose cells. BMC provides therapeutic concentrations of these cell types which is the key to desirable patient outcomes.
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